Bruce Analytic Consulting Services, LLC

Alternative text for describing the image displayed

Bruce Analytic Consulting Services, LLC

Generating Rigorous Evidence to Improve Population Health

Learn More
Scott Graham

About Bruce Analytic Consulting Services

Bruce Analytic Consulting Services brings over 20 years of expertise in health data analytics, epidemiology, and outcomes research to clients across pharmaceutical, biotech, payer, and academic settings. Founded by Liana D. Bruce, PhD, MSPH, our firm delivers senior-level, hands-on research support from study conception through publication. We specialize in generating credible evidence that informs critical decisions to improve population health outcomes.

With expertise in SAS, R, and Python programming, large-scale claims data analysis, and regulatory-aligned deliverables, we partner with clients to design rigorous studies and produce publication-ready results. Our comprehensive approach ensures that every project meets the highest standards of scientific rigor and regulatory compliance, enabling our clients to make evidence-based decisions with confidence.

Our Services

John

Real-World Evidence (RWE) Studies & Data Analysis

Comprehensive RWE study design and data analysis services, including sample size calculation, power analysis, and statistical programming using SAS, R, and Python. We leverage large-scale claims data to generate credible, real-world evidence that supports regulatory submissions and clinical decision-making.

Gabrielle Henderson

Health Economics & Outcomes Research (HEOR)

Full-spectrum HEOR consulting including study design, economic modeling, and outcomes analysis. We help clients understand the clinical and economic value of interventions, supporting health policy decisions and payer negotiations with robust, evidence-based analyses.

LinkedIn Sales Solutions

Regulatory Documentation & Publication Support

End-to-end support for regulatory submissions, IRB documentation, research proposals, grant development, and manuscript preparation. From RFP development to journal submission support and authorship consultation, we ensure your research meets regulatory standards and reaches publication.

Publications

Original Research (25+ peer-reviewed) – click to expand
  1. Hong M, Esse T, Vadhariya A, Gallardo E, Fosshat MA, Mamvou J, Bruce L, Serna O, Abughosh S. Evaluating success factors of a medication adherence tracker pilot program in improving Part D medication adherence metrics in a Medicare Advantage plan: importance of provider engagement. Journal of Managed Care & Specialty Pharmacy. 2020;26:662-667.
  2. Swanson AJ, Castel LD, McKenna PA, Shen YA, Sagar B. Integration of the National Comprehensive Cancer Network (NCCN) distress screening tool as a guidepost for telephonic oncology case management. Professional Case Management. 2019;24:148-154.
  3. Castel LDH. Introducing the first articles of the veterans and military patient-related health outcomes thematic series. Patient Related Outcome Measures. 2019;10:81-82.
  4. Mann A, Esse TW, Serna O, Castel LD, Abughosh SM. Effectiveness of mailed letters to improve medication adherence among Medicare Advantage plan participants with chronic conditions. Patient Preference and Adherence. 2019;13:37-46.
  5. Bruce LD, Wu JS, Lustig SL, Russell DW, Nemecek DA. Loneliness in the United States: a 2018 national panel survey of demographic, structural, cognitive, and behavioral characteristics. American Journal of Health Promotion. 2019;33:1123-1133.
  6. Manocchia M, Donatell RC, Brown R, Bruce LD. Peer benchmarking and norm-based scoring to improve telephonic health coaching quality. Joint Commission Journal on Quality and Patient Safety. 2019;45:613-619.
  7. Everett B, Castel LD, McGinnis M, Beresky A, Cane RC, Cooper T, Davda RK, Farmer D, John SM, Sollars DL, Rausch JF. Economic and clinical outcomes resulting from the stage 4 chronic kidney disease case management quality improvement initiative. Professional Case Management. 2017;22:291-298.
  8. Sagar B, Lin YS, Castel LD. Cost drivers for breast, lung, and colorectal cancer care in a commercially insured population over a 6-month episode: an economic analysis from a health plan perspective. Journal of Medical Economics. 2017;20:1018-1023.
  9. Mino DE, Munterich JE, Castel LD. Lumbar fusion surgery for degenerative conditions is associated with significant resource and narcotic use 2 years postoperatively in the commercially insured: a medical and pharmacy claims study. Journal of Spine Surgery. 2017;3:141-148.
  10. Nelms JA, Castel L. A systematic review and meta-analysis of randomized and nonrandomized trials of clinical Emotional Freedom Techniques (EFT) for the treatment of depression. Explore. 2016;12:416-426.
  11. Castel LD, Wallston KA, Saville BR, Alvarez JR, Shields BD, Feurer ID, Cella D. Validity and reliability of the Patient-Reported Arthralgia Inventory: validation of a newly-developed survey instrument to measure arthralgia. Patient Related Outcome Measures. 2015;6:205-214.
  12. Meyers AG, Salanitro A, Wallston KA, Cawthon C, Vasilevskis EE, Goggins KM, Davis CM, Rothman RL, Castel LD, Donato KM, Schnelle JF, Bell SP, Schildcrout JS, Osborn CY, Harrell FE, Kripalani S. Determinants of health after hospital discharge: rationale and design of the Vanderbilt Inpatient Cohort Study (VICS). BMC Health Services Research. 2014;14:10.
  13. Goggins KM, Wallston KA, Nwosu S, Schildcrout JS, Castel L, Kripalani S, VICS. Health literacy, numeracy, and other characteristics associated with hospitalized patients’ preferences for involvement in decision making. Journal of Health Communication. 2014;19 Suppl 2:29-43.
  14. Castel LD, Hartmann KE, Mayer IA, Saville BR, Alvarez J, Boomershine CS, Abramson VG, Chakravarthy AB, Friedman DL, Cella DF. Time course of arthralgia among women initiating aromatase inhibitor therapy and a postmenopausal comparison group in a prospective cohort. Cancer. 2013;119:2375-2382.
  15. Bode RK, Hahn EA, DeVellis R, Cella D, PROMIS Social Domain Working Group. Measuring participation: the Patient-Reported Outcomes Measurement Information System experience. Archives of Physical Medicine and Rehabilitation. 2010;91:S60-S65.
  16. Hahn EA, DeVellis RF, Bode RK, Garcia SF, Castel LD, Eisen SV, Bosworth HB, Heinemann AW, Rothrock N, Cella D, PROMIS Cooperative. Measuring social health in the Patient-Reported Outcomes Measurement Information System (PROMIS): item bank development and testing. Quality of Life Research. 2010;19:1035-1044.
  17. Carey TS, Freburger JK, Holmes GM, Castel L, Darter J, Agans R, Kalsbeek W, Jackman A. A long way to go: practice patterns and evidence in chronic low back pain care. Spine. 2009;34:718-724.
  18. Freburger JK, Holmes GM, Agans RP, Jackman AM, Darter JD, Wallace AS, Castel LD, Kalsbeek WD, Carey TS. The rising prevalence of chronic low back pain. Archives of Internal Medicine. 2009;169:251-258.
  19. Castel LD, Freburger JK, Holmes GM, Scheinman RP, Jackman AM, Carey TS. Spine and pain clinics serving North Carolina patients with back and neck pain: what do they do, and are they multidisciplinary? Spine. 2009;34:615-622.
  20. Freburger JK, Carey TS, Holmes GM, Wallace AS, Castel LD, Darter JD, Jackman AM. Exercise prescription for chronic back or neck pain: who prescribes it? who gets it? what is prescribed? Arthritis and Rheumatism. 2009;61:192-200.
  21. Castel LD, Williams KA, Bosworth HB, Eisen SV, Hahn EA, Irwin DE, Kelly MAR, Morse J, Stover A, DeWalt DA, DeVellis RF. Content validity in the PROMIS social-health domain: a qualitative analysis of focus-group data. Quality of Life Research. 2008;17:737-749.
  22. Castel LD, Saville BR, DePuy V, Godley PA, Hartmann KE, Abernethy AP. Racial differences in pain during 1 year among women with metastatic breast cancer: a hazards analysis of interval-censored data. Cancer. 2008;112:162-170.
  23. Castel LD, Abernethy AP, Li Y, DePuy V, Saville BR, Hartmann KE. Hazards for pain severity and pain interference with daily living, with exploration of brief pain inventory cutpoints, among women with metastatic breast cancer. Journal of Pain and Symptom Management. 2007;34:380-392.
  24. DePuy V, Anstrom KJ, Castel LD, Schulman KA, Weinfurt KP, Saad F. Effects of skeletal morbidities on longitudinal patient-reported outcomes and survival in patients with metastatic prostate cancer. Supportive Care in Cancer. 2007;15:869-876.
  25. Weinfurt KP, DePuy V, Castel LD, Sulmasy DP, Schulman KA, Meropol NJ. Understanding of an aggregate probability statement by patients who are offered participation in Phase I clinical trials. Cancer. 2005;103:140-147.
  26. Gaskin DJ, Weinfurt KP, Castel LD, DePuy V, Li Y, Balshem A, Benson A, Burnett CB, Corbett S, Marshall J, Slater E, Sulmasy DP, Van Echo D, Meropol NJ, Schulman KA. An exploration of relative health stock in advanced cancer patients. Medical Decision Making. 2004;24:614-624.
  27. Weinfurt KP, Castel LD, Li Y, Timbie JW, Glendenning GA, Schulman KA. Health-related quality of life among patients with breast cancer receiving zoledronic acid or pamidronate disodium for metastatic bone lesions. Medical Care. 2004;42:164-175.
  28. Weinfurt KP, Castel LD, Li Y, Sulmasy DP, Balshem AM, Benson AB, Burnett CB, Gaskin DJ, Marshall JL, Slater EF, Schulman KA, Meropol NJ. The correlation between patient characteristics and expectations of benefit from Phase I cancer clinical trials. Cancer. 2003;98:166-175.
  29. Meropol NJ, Weinfurt KP, Burnett CB, Balshem A, Benson AB, Castel L, Corbett S, Diefenbach M, Gaskin D, Li Y, Manne S, Marshall J, Rowland JH, Slater E, Sulmasy DP, Van Echo D, Washington S, Schulman KA. Perceptions of patients and physicians regarding phase I cancer clinical trials: implications for physician-patient communication. Journal of Clinical Oncology. 2003;21:2589-2596.
  30. Castel LD, Timbie JW, Sendersky V, Curtis LH, Feather KA, Schulman KA. Toward estimating the impact of changes in immigrants’ insurance eligibility on hospital expenditures for uncompensated care. BMC Health Services Research. 2003;3:1.
  31. Seils DM, Castel LD, Curtis LH, Weinfurt KP. Welfare reform and Latinas’ use of perinatal health care. American Journal of Public Health. 2002;92:699-700.

    Business hours: Monday through Friday, by appointment during business hours

    © 2026 Bruce Analytic Consulting Services, LLC. All rights reserved.